Jennifer Aniston and Vince Vaughn reportedly spent their Thanksgiving holed up together at a luxurious US resort.

The former "Friends" beauty and the heartthrob actor - who have denied their romance despite being spotted kissing several times in recent months - are said to have checked in to the plush Sanctuary resort in Paradise Valley, Arizona.

An onlooker told America's New York Post the pair kept their stay low key to avoid attention. The source revealed: "They seemed to keep a pretty low profile."

"For instance, I didn't see them at all hanging around the visually arresting infinity pool, a focal point for other guests. However, someone told me they did appear in the restaurant for dinner at least."

Meanwhile, Jennifer's ex-husband Brad Pitt and new lover Angelina Jolie - a United Nations goodwill ambassador - spent Thanksgiving visiting survivors of the Pakistan earthquake.

The pillow-lipped beauty - who has two adopted children, Maddox and Zahara, reportedly wanted to see how survivors are being cared for - and took hunky Brad with her.